摘要
目的:探讨了冠心病患者血清超敏C反应蛋白(hs-CRP)和E-选择素(E-Selectin)水平的变化及意义。方法:应用免疫比浊法检测hs-CRP,ELISA法检测E-Selectin水平对58例冠心病患者进行了血清hs-CRP,E-Selectin水平检测。其中稳定型心绞痛25例,不稳定型心绞痛20例,急性心肌梗死13例,并以35名正常健康人作比较。结果:冠心病患者血清hs-CRP和E-Selectin水平明显高于正常人组(P<0.01),急性心肌梗死组和不稳定型心绞痛组有明显高于稳定型心绞痛组(P<0.01),冠心病组血清hs-CRP、E-Selectin水平与冠状动脉狭窄程度无明显相关性(P>0.05)。结论:血清hs-CRP和E-Selectin水平的变化与冠心病的发生、发展有关,但与冠状动脉狭窄程度无关。
Objective To investigate the significance of determination of serum contents of hs - CRP and E - Selectin in patients with coronary heart diseases （CHD）. Methods Serum hs - CRP Contents were determined with immune - turbidity and E - Selectin contents were determined with ELISA in 58 patients with CHD （35SAP, 20UAP, 13AMI） and 35controls. Results Serum levels of hs -CRP and E -Seleetin in CAD patients were significantly higher than those in controls （P 〈0.01 ）. Among the CHD patients, the levels of hs -CRP and E- selectin in AMI and UAP groups were significantly higher than those in SAP group（ P 〈0.01 ）. There was no correlationship between degree of stenosis of coronary artery and serum levels of hs - CRP and E - Selectin （P 〉 0.05 ）. Conclusion The serum levels of hs - CRP and E - Selectin were correlated to the development of CAD, but not to the coronary artery callbets.
出处
《放射免疫学杂志》
CAS
2007年第3期276-277,共2页
Journal of Radioimmanology
关键词
冠心病
超敏C-反应蛋白
E-选择素
稳定性心绞痛
不稳定型心绞痛
急性心肌梗死
coronary heart diseases, hyper sensitive C - reactive protein （ hs - CRP）, E - Selectin, stable angina pectoris （ SAP）, unstable angina pectofis （ UAP）, acute myocardial infaction （ AMI ）
