摘要
目的观察早期连续性血液净化治疗多器官功能障碍综合征的疗效及对生化指标的影响。方法纳入45例多器官功能障碍综合征患者,在早期进行连续性血液净化治疗,治疗后观察患者临床指标及生化指标变化、APACHEⅡ和MODS评分改善情况。结果所有患者在治疗过程中,多巴胺剂量逐渐减少,心率、平均动脉压及氧合指数均较前改善,差异有统计学意义(P<0.05)。肌酐、尿素氮治疗前后比较差异有统计学意义(P<0.05),总胆红素和游离胆红素比较差异无统计学意义(P>0.05)。APACHEⅡ及MODS评分治疗前后比较差异有统计学意义(P<0.05)。结论早期连续性血液净化治疗多器官功能障碍综合征患者有改善预后的作用,患者耐受性较好。
Objective To observe the effect of early CBP treat MODS and the change of biochemical parameters. Methods All of 45 cases of MODS patients, at an early stage of CBP therapy, were observed biochemical changes,clinical indicators, APACHE Ⅱ score, MODS improve after treatment. Results All patients in the treatment process, gradually reduced the dose of dopamine, heart rate, mean arterial pressure and oxygenation index improved than before, the difference was significant （P〈0.05）. Creatinine, blood urea nitrogen before and after treatment the difference was statistically significant （/9〈0.05）, total bilirubin and free bilirubin difference was not statistically significant （P〉0.05）. APACHE Ⅱ and MODS score differences before and after treatment were more significant （P〈0.05）. Conclusion Early CBP therapy in patients with MODS can improve the prognosis, the patient tolerated well.
出处
《中国现代医生》
2012年第1期41-42,共2页
China Modern Doctor
关键词
早期连续性血液净化
多器官功能障碍综合征
疗效
Early continuous blood purification
Multiple organ dysfunction syndrome
Effect
