摘要
目的了解2010年山东省30所医院来源于重症监护病房(ICU)临床分离病原菌的耐药性。方法采用纸片扩散法(K-B法)对临床分离菌株进行药敏试验。结果共收集临床分离病原菌10 627株,其中革兰阴性菌9116株,革兰阳性菌1511株;铜绿假单胞菌对亚胺培南和美罗培南的耐药率分别为50.8%、50.9%,鲍氏不动杆菌对亚胺培南和美罗培南的耐药率分别为80.0%、78.7%。结论山东省ICU临床分离病原菌以革兰阴性菌为主,细菌的耐药呈增长趋势,必须加以重视。
OBJECTIVE To investigate the drug resistance of pathogens isolated from ICU of 30 hospitals in Shandong province in 2010.METHODS The antimicrobial susceptibility of 10 627 clinical isolates was tested according to an agreed protocol using Kirby-Bauer（K-B） method.RESULTS Of the 10627 clinical isolates of pathogens,there were 9116 strains of gram-negative bacteria,1511 strains of gram-positive bacteria.The resistance rates of Pseudomonas aeruginosa to imipenem and meropenem were 56.9% and 57.2%,the resistance rates of Acinetobacter baumannii to imipenem and meropenem were 80.0% and 78.7%.CONCLUSION Gram-negative bacteria are the major pathogens isolated from ICU in Shandong province.Bacterial resistance presents an upward trend,which is worthy of the attention.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第2期374-377,共4页
Chinese Journal of Nosocomiology
关键词
重症监护病房
耐药性
细菌分布
Intensive Care Unit
Resistance
Bacteria distribution
