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血清降钙素原水平在尿路感染中的定位作用研究 被引量:4

Study on Orientating Function of Serum Procalcitonin Level in Urinary Tract Infection
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摘要 目的探讨血清降钙素原(PCT)在尿路感染中的定位作用。方法选取尿路感染患者106例,同期健康体检者100例,用化学发光免疫法测定血清中的PCT和C-反应蛋白(CRP)水平,同时检测患者外周血白细胞计数(WBC)。结果上尿路感染组患者血清PCT水平明显高于下尿路感染患者组(P<0.01),PCT对上尿路感染诊断的敏感性为81.1%,特异性为85.5%,阳性预测值为80.3%,阴性预测值为92.5%,均高于CRP和WBC。结论血清PCT水平的测定对尿路感染有定位作用。 Objective To explore the location role of serum prccalcitonin (PCT) in the diagnosis of urinary tract infection (UTI). Methods One hundred and six patients with urinary tract infection and 100 health examinees were enrolled in this study. The serum PCT and C- reactive protein (CRP) levels were measured by chemiluminescent immunoassay; meanwhile, peripheral white blood cells were counted. Results The serum level of PCT in upper urinary tract infection group was significantly higher than that in lower urinary tract infection group (P〈0.01). The sensitivity and specificity of PCT in diagnosis of upper urinary tract infection were 81.1% and 85.5% respectively, positive predictive value was 80.3% and negative predictive value was 92.5 %, which were all higher than CRP and WBC. Conclusions The serum level of PCT can be used as a marker to differentially diagnose the upper and lower urinary tract infections.
出处 《实用预防医学》 CAS 2012年第1期121-122,共2页 Practical Preventive Medicine
关键词 降钙素原 C-反应蛋白 白细胞计数 尿路感染 Procaleitonin CRP WBC Urinary tract infection
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