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识别疟色素的模式识别受体

Pattern Recognition Receptors for Recognizing Hemozoin
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摘要 疟色素是疟原虫消化宿主血红蛋白产生的副产物,能激发宿主的先天性炎症反应。然而对于疟色素是如何被宿主模式识别受体识别,各个研究者的实验结果和结论不尽相同。本文综述了近期该研究领域的一些进展。 Hemozoin(malaria pigment)is a byproduct of malaria parasites due to hemoglobin digestion,which can stimulate host′s innate inflammatory responses.However,data from different studies are controversial about how hemozoin is recognized by the host′s pattern recognition receptors.This article reviews the recent progress in the area.
作者 钱锋 徐沪济
出处 《中国寄生虫学与寄生虫病杂志》 CAS CSCD 北大核心 2011年第6期477-479,共3页 Chinese Journal of Parasitology and Parasitic Diseases
基金 国家重点基础研究发展计划(973计划)项目(No.2007-CB513105) 国家自然科学基金(No.81072498)~~
关键词 疟色素 TOLL样受体 NOD样受体 Hemozoin Toll-like receptor NOD-like receptor
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参考文献14

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