摘要
目的探讨热毒宁注射液联合干扰素治疗小儿轮状病毒性肠炎的疗效和安全性。方法 30例轮状病毒性肠炎小儿患者随机分为治疗组和对照组。治疗组静脉滴注热毒宁注射液并肌肉注射干扰素进行治疗,对照组采用单独肌肉注射干扰素进行治疗。连续治疗3 d后对两组患者退热时间、止吐时间、止泻时间、总病程、治疗有效率以及不良反应进行比较分析。结果治疗组患者退热时间、止吐时间、止泻时间及总病程较对照组显著缩短(P<0.05)。治疗组疗效优于对照组(P<0.05)。治疗组的总有效率(93.33%)也高于对照组(60.00%)(P<0.05)。治疗组未出现不良反应,对照组出现发热2例,烦躁2例,经相应处理后患者症状缓解。结论热毒宁注射液联合干扰素治疗小儿轮状病毒性肠炎疗效显著,安全性可靠,值得临床推广使用。
Objective To explore the toxicity and efficacy of reduning injection combined with interferon in the treatment of rotaviral enteritis in children. Methods Thirty children with rotaviral enteritis were randomly divided into control group and therapy group. Patients in the control group were treated with intramuscular injection of inter- feron. Patients in the therapy group were treated with intravenous drip of reduning injection combined with intramus- cular injection of interferon. After three days of treatment, defervescence time, vomiting time, diarrhea time, course of disease, effective rate and adverse reaction were antdyzed. Results Compared with control group, defervescence time, vomiting time, diarrhea time and course of disea,~e significantly reduced in the therapy group （ P 〈 0.05 ）. The effective rate in the therapy group and control group were 93.33 % and 60. 00 %, respectively （ P 〈 0. 05 ）. The side effect was not found in therapy group. In the control group, 2 children had fever symptom, 2 children had irritability symptom. Conclusion Reduning injection combined with interferon is feasible and effective in the treatment in chil- dren of rotaviral enteritis.
出处
《中国临床新医学》
2011年第12期1163-1165,共3页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
