摘要
目的探讨原发性肾病综合征(PNS)发生医院感染的危险因素。方法根据275例肾病综合征患者临床特征与医院感染的关系,进行病例对照分析。结果 275例PNS患者发生医院感染89例,感染率为32.4%,中位感染发生时间为入院后28d;89例医院感染患者检出病原菌20株,检出率22.5%;感染组病例与非感染组在年龄、性别、病程、是否使用激素上差异无统计学意义,与血清白蛋白含量、IgG含量呈负相关,与血肌酐及尿蛋白水平呈正相关。结论血清白蛋白含量、IgG含量、血肌酐及尿蛋白水平有望作为评价PNS发生医院感染的危险因素。
OBJECTIVE To investigate the risk factors of nosocomial infection in patients with nephrotic syndrome. METHODS A total of 275 PNS cases were analyzed with clinical features and association of and nosocomial infection. RESULTS Totally 89 of 275 cases occurred nosocomial infections in PNS patients with an incidence rate of 32.4%, with a median time of infection was 28 days after admission, the infection group of patients with and without infection in age, gender, disease duration, whether the use of hormones was no significant difference while serum albumin, IgG were negatively correlated, serum creatinine and urine protein levels were positively correlated with infection. CONCLUSION Serum albumin, IgG levels, serum creatinine and urineprotein levels are expected tO PNS as an evaluation of risk factors of nosocomial infection.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第24期5206-5208,共3页
Chinese Journal of Nosocomiology
关键词
肾病综合症
医院感染
易感因素
Renal syndrome
Nosocomial infection
Risk factor
