摘要
目的建立防栓胶囊的质量标准。方法采用薄层色谱法对防栓胶囊中的川芎、石菖蒲进行定性鉴别;采用高效液相色谱法测定2,3,5,4'-四羟基二苯乙烯-2-O-β-D葡萄糖苷的含量。结果薄层色谱鉴别斑点清晰,专属性强;2,3,5,4'-四羟基二苯乙烯-2-O-β-D葡萄糖苷的线性范围为0.005 030～0.040 240 mg/mL(r=0.999 8),平均回收率为100.23%,RSD为0.71%。结论该方法快速、准确、重现性好,适用于防栓胶囊的质量控制。
Objective To establish the quality standard of Fangshuan capsule.Methods Chuanxiong Rhizoma and Acori tatarinowii Rhizoma was identified by TLC;and the content of 2,3,5,4＇-tetra-hydroxyl diphenyl ethylene-2-O-β-D-glucoside was determined by HPLC.Results The spots of TLC were clear and specific;Linear range of 2,3,5,4＇-tetra-hydroxyl diphenyl ethylene-2-O-β-D-glucoside was good in 0.005 030 ～0.040 240 mg/mL（r = 0.999 8）,the average recovery was 100.23%,and RSD was 0.71%.Conclusion This method was rapid,accurate,reproducible and could apply to the quality control of Fangshuan capsule.
出处
《现代中药研究与实践》
CAS
2011年第6期78-80,共3页
Research and Practice on Chinese Medicines
