摘要
目的 比较每日补铁与每周补铁改善铁缺乏儿童血清铁蛋白水平的效果.方法 通过检索电子数据库、手工检索相关期刊书籍、并通过查找参考文献进行全面的文献检索;使用Cochrane EPOC制定的标准对纳入研究质量进行了评价;并对各结局的纳入研究进行Meta分析.结果 每日补铁比每周补铁使铁缺乏儿童血清铁蛋白浓度增加0.62μg/L(95%CI:0.38~0.85,P〈0.01).结论 每日补铁比每周补铁对增加铁缺乏儿童血清铁蛋白含量更为有效.
Objective To compare the effects of daily iron supplementation and weekly iron supplementation on promoting serum ferritin level in iron deficient children. Methods Comprehensive literature retrieval was performed via searching electronic databases, bibliographies of books and relevant journals, and reviewing references and citations. Criteria from Coehrane EPOC review group were used to assess the quality of included studies. A meta-analysis was done on included studies. Results The serum ferritin level improved by daily iron supplementation increased 0. 62 μg/L compared with that improved by weekly iron supplementation (95 % CI:0. 38 - 0. 85,P 〈 0. 01 ). Conclusion Daily iron supplementation is superior to weekly iron supplementation in improving serum ferritin for iron deficient children.
出处
《中国妇幼健康研究》
2011年第6期719-722,共4页
Chinese Journal of Woman and Child Health Research
关键词
铁缺乏
每日补铁
每周补铁
血清铁蛋白
META分析
iron deficiency
daily iron supplementation
weekly iron supplementation
serum ferritin
recta-analysis