摘要
目的:探讨间隔补铁治疗小儿缺铁性贫血的临床意义。方法:将46例缺铁性贫血的小儿随机分为两组,各23例。组1每周2天给药(间隔3天),组2每天给药,经12周补铁治疗,以血红蛋白(Hb)、血清铁蛋白(SF)作为评价治疗效果的血液学指标,并观察不同补铁方式的不良反应发生情况。结果:两组在治疗后Hb、SF值均有不同程度的上升,与治疗前相比,差异有统计学意义(P<0.01);治疗后两组Hb、SF值差异无统计学意义(P>0.05);每周2天给药组不良反应明显减少。结论:间隔补铁在纠正贫血上与每日补铁同样有效且不良反应少。
Objective:To investigate the clinical significance of intermittent iron treatment on children with iron deficiency anemia.Methods:46 children with iron deficiency anemia were randomly divided into two groups with 23 cases in each.In group 1drug administration for two times every week(3 days apart).In group 2 drug administration for every day.After12 weeks of iron therapy, using hemoglobin(Hb) and serum ferritin(SF) as blood index to evaluate the therapeutic effect.Then observe the occurrence of adverse reactions in different iron supplements.Results:After treatment,Hb and SF in two groups both increased in varying degrees when compared before the treatment,and the difference were statistically significant(P<0.01).The value of Hb and SF in two groups had no difference after treatment(P>0.05).Drug administration for two times every week in group 1 can reduce side effect significantly.Conclusion:In the correction of anemia,intermittent iron and daily iron supplement had equally effect and less side effects.
关键词
缺铁性贫血
间隔补铁
每天补铁
Anemia
Iron deficiency
Intermittent iron
Daily iron
