摘要
目的:了解罂粟碱在不同给药途径下对肢体血管修复术后皮肤温度的影响。方法:选择肢体损伤后需行血管修复指(趾)体才能存活和皮瓣移植修复皮缺损的患者120例,随机分为治疗组A(口服罂粟碱)、治疗组B(肌内注射罂粟碱),治疗组C(静脉注射罂粟碱)和对照组(不给予任何血管扩张药)各30例。用红外线皮温观察仪持续观察血管修复术后患者的肢体温度,对比罂粟碱不同给药途径对皮温差的影响、患者血管危象与指(趾)体皮瓣成活率、药物起效时间和持续时间。结果:治疗组应用罂粟碱后可升高患侧肢体的皮温,减少肢体间的皮温差(P<0.05);治疗组血管危象发生率较对照组低,但无统计学意义(P>0.05);指(趾)体和皮瓣成活率较对照组高,亦无统计学意义(P>0.05);不同给药途径下,静脉给药后皮肤温度升高速度最快,肌内注射次之,口服最慢,但持续时间相反(均P<0.05)。结论:不同的罂粟碱给药途径均可提高肢体损伤血管修复术后患侧的皮肤温度,其中以静脉给药途径最佳,肌内注射次之。
Objective：To discuss the impact of difference narceine medication pathway on skin temperature after blood vessel prosthesis of limp injury.Methods：120 patients with limp injury were divided into treatment group A（take oreally narceine）,treatment group B（intramuscular injection narceine）,treatment group C（mainline narceine） and control group（without vasodilator）,30 patients in each group.To observe the limp temperature after blood vessel prosthesis by infrared skin temperature viewer,to observe the correlation of injury limp survival rate and vascular stria occurate and skin temperature change after different pathway.Results：After used narceine the injury limp skin temperature was improved and difference of skin temperature was reduced（P0.05）.The vascular stria occurate of treatment group was lower than that of control group,while the limp survival rate wan higher than that of control group,but there were no statistical sense（all P0.05）.The fastest rise of skin temperature was mainline narceine,the next was intramuscular injection narceine,the last was take oreally narceine,but the continue time was contrary.Conclusion：Narceine with different given pathway could improve skin temperature after blood vessel prosthesis of limp injury,mainline narceine is the best Medication pathway,the next is intramuscular injection.
出处
《护理实践与研究》
2011年第18期1-3,共3页
Nursing Practice and Research
基金
佛山市科技发展专项资金项目(200808038)
关键词
罂粟碱
给药途径
皮肤温度
影响
Narceine
Medication pathway
Skin temperature
Influence
