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载脂蛋白AI、B和脑血栓,脑出血关系的调查

Investigation of Association between Apolipoprotein AI,B and Cerebral Thrombosis,Hemorrhage
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摘要 140例脑中风病人和103例同龄正常人的血清,同时用免疫透射比浊法测定其 Apo-AI 和 B.结果病人组 Apo-AI 水平显著低于正常人组,Apo-B 显著高于正常人组,Ago-AI/Apo-B 的比值低于正常人组,均有统计学意义,将140例中脑血栓和脑出血病人分别和正常人比较,Apo-AI 水平及 Apo-AI/Apo-B 的比值,脑出血病人组和正常组的差异无统计学意义,而 Apo-B 水平的差异有显著的统计学意义。脑血栓病人组和正常人组比,Apo-AI,B 的水平及 Aop-AI/Apo-B 的比值之差异均有极著显的统计学意义,Apo-AI 水平,正常人组和脑出血病人组,组内男女之间的差异有统计学意义,而 Apo-B 的差异无统计学意义。脑血栓病人组内男女之间,Apo-AI 和 B 水平的差异均无统计学意义,本文认为 Apo-AI,B 的水平及 Apo-AI/Apo-B 的比值在病人组和正常人组的显著差异可看作脑血栓的危险因素,应进一步探索其是否能作为预测疾病的指标。 The sera of 140 patients with stroke and 103 healthy controls of the same age were detected by immune-transmission turbidity method.There suits were as follows:Apo-AI level of the pa- tient group was significantly lower than that of the healthy group,Apo-B level was significantly higher than that of the healthy group.and the value of Apo-AI/Apo-B was signifcantly lower than that of the healthy group.There were statistcal significance in all the differences.The 140 cares of patients with cerebral thrombosis or hemorrhage were compared with the healthy group. There was no statistical significaance in the differences of Apo-AI level and value of Apo-AI/ Apo-B between hemorrhage and healthy groups,but there was statistical significance in the dif- ference of Apo-B.There was marked statistical significance in the differences of Apo-AI,B level and value of Apo-AI/Apo-B between thrombosis and healthy groups.This paper shows that the significant differences of Apo-AI,B level and value of Apo-AI/Apo-B between pa- tients and hralthy groups should be considered as risk factors of cerebral thrombosis.It should be further investigated whether the differences we found can be used as predictors forcerebal throm- bosis.
出处 《广州医学院学报》 1990年第3期24-28,共5页 Academic Journal of Guangzhou Medical College
关键词 脑血栓 脑出血 载脂蛋白 Apo—AI B 免疫透射比浊法 cerebral thrombosis cerebral hemorrhage Apo-AI Apo-B immunotransmission turbidety method.
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  • 1李洵桦,刘焯霖,梁秀龄.动脉硬化性脑血栓形成患者血清高密度脂蛋白亚组分水平研究[J]中国神经精神疾病杂志,1988(05). 被引量:1
  • 2吴满平.载脂蛋白基因和功能研究[J]生理科学进展,1988(02). 被引量:1

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