摘要
目的分析医院药品不良反应(ADR)的发生规律和特点。方法对2008年至2010年上报的283例药品不良反应分别从患者性别、年龄、报告科室、给药途径、用药情况、药品不良反应涉及系统或器官及临床表现等方面进行统计、分析。结果 283例药品不良反应报告中,由干内科上报最多(47例,占16.61%);抗感染药物引起的比例最高(占49.82%),其次为中药注射剂(占17.31%);给药途径中静脉滴注引起的249例,占87.99%;临床表现以皮肤及其附件损害最为常见,占45.58%。结论临床用药应注意抗感染药物与中药注射剂的合理使用,减少静脉给药,并考虑老年人的体质特点,以减少或避免药品不良反应的发生。
Objective To investigate and analyze the regular pattern and characteristics of adverse drug reaction（ADR） in our hospital from 2008 to 2010.Methods Two hundred and eighty-three ADR cases reported in our hospital were analyzed retrospectively in respect of patients＇sex and age,reporting department,routes of administration,use of drugs,systems and organs involved in ADR and its clinical manifestations,etc.Results Forty-seven cases were submitted by cadres medical department,accounting for 16.61%.Anti-infective drugs（49.82%） occupied the highest proportion in ADR,followed by traditional Chinese medicine injection（17.31%）.Two hundred and forty-nine cases were induced by intravenous route,accounting for 87.99%.The major systems involved were skin and its appendages（45.58%）.Conclusion It is important to pay attention to the rational use of anti-infective and traditional Chinese medicine injection,decreasing the intravenous route and considering the characteristics of the old people＇s constitutions in order to reduce or avoid ADR.
出处
《中国药业》
CAS
2011年第21期42-43,共2页
China Pharmaceuticals
