摘要
本文讨论消除符合(一级并行)米氏过程药物的多剂量周期性血管外或血管内给药稳态性质分析的数值解法。
In this paper,we have proposed a numerical method to analyse the properties of the steady-state of the plssma concentration of drugs obeying parallel first order and Michaelis-Menten clearance kinetics,inputed by multiple extravenous or intravenous administration.
出处
《生物数学学报》
CSCD
北大核心
1996年第4期210-214,共5页
Journal of Biomathematics
关键词
药物动力学
给药方案
米氏消除
Pharmacokinetics,Dosage regimen,Michaelis-Menten clearance