摘要
观察２１例冠心病患者及正常对照组的空腹血浆甘油三酯（ＴＧ）、总胆固醇（ＴＣ）、低密度脂蛋白胆固醇（ＬＤＬＣ）、高密度脂蛋白胆固醇（ＨＤＬＣ），红细胞膜Ｎａ＋Ｋ＋ＡＴＰ酶、Ｃａ２＋ＡＴＰ酶，Ｍｇ２＋ＡＴＰ酶及红细胞内Ｃａ２＋浓度（［Ｃａ２＋］）的变化。发现冠心病组ＴＧ，ＴＣ，ＬＤＬＣ及红细胞内［Ｃａ２＋］高于对照组；而血浆ＨＤＬＣ，红细胞膜Ｎａ＋Ｋ＋ＡＴＰ酶与Ｃａ２＋ＡＴＰ酶活性低于后者；Ｍｇ２＋ＡＴＰ酶无变化；Ｎａ２＋Ｋ＋ＡＴＰ酶，Ｃａ２＋ＡＴＰ酶分别与血浆ＴＧ，ＴＣ和ＬＤＬＣ呈负相关，与血浆ＨＤＬＣ呈正相关。根据测定结果。
Fasting plasma triglyceride(TG), total cholesterol(TC), low density lipoprotein cholesterol(LDL C), high density lipoprotein cholesterol(HDL C), activities of erythrocyte membrane Na + K + ATPase, Ca 2+ ATPase, Mg 2+ ATPase, and intraerythrocytic calcium concentration were examined in 21 patients with coronary heart disease(CHD) and 21 normal controls. It was found that the plasma contents of TG, TC, LDL C and intraerythrocytic [Ca 2+ ] in patients with CHD were much higher while plasma contents of HDL C, activities of erythrocyte membrane Na + K + and Ca 2+ ATPase were much lower than those of normal controls. Mg 2+ ATPase activity showed no significant difference between these two groups. The activities of erythrocyte membrane Na + K + and Ca 2+ ATPase were negatively correlated with plasma TG, TC, LDL C levels, respectively, and positively correlated with plasma HDL C. The possible pathogenic mechanism is discussed on the basis of our results.
出处
《中南大学学报（医学版）》
CAS
CSCD
1999年第1期71-73,共3页
Journal of Central South University ：Medical Science
