摘要
按冠脉主要分支最大狭窄程度不同将冠心病（ＣＨＤ）分为明显狭窄 组（ＯＳ）和杉反狭且（ＭＳ），探讨血脂（ＣＨ、Ｔ Ｇ、ＨＤＬ－ｃｈ）、载脂蛋白（ａｐｏＡＩ、 ａｂｏＢ）及纤维蛋白原（Ｆｇ）对红细胞流变特性的作用。结呆显示：ＣＨＤ两组的红细 胞集率升高与Ｆｇ相关；ＴＧ可能是影响红细胞变形指数（ＤＩ）重要因素之一。随冠 脉狭窄程度加重，ＨＤＬ－ｃｈ、ａｐｏＡＩ、ａｐｏＢ对红细胞流变特性的影响也发生变化。
According to the extent of coronary maximal stenoses, 29 coronary heart disease (CHD) patients were classifiedsnto(Ⅰ) obvious stenoses group (OS narrowing in luminal diameter ≥ 50% n = 15), (Ⅱ) mild stenoses group (MS narrowing in luminal diameter ＜ 50% n = 14). The results showed Rrythrocyte deformability index(DI), erythrocyte aggregation rate (EAR), triglyceride (TG), apolipoprotein A1(apoAI), high -density lipoprotein cholesterol (HDL-ch) and fibrinogoen (Fg) in OS changed significantly as compared with MS (p ＜ 0. 05). The increasing of EAR was related to the level of Fg in MS and OS; Tg may effect erythrocyte deformability in both groups. With the stenoses aggravting, the effects of HDL-ch, apoAI and apoB on erythrocyte rheological properties changed accordingly.
出处
《中国血液流变学杂志》
CAS
1997年第4期6-9,共4页
Chinese Journal of Hemorheology
关键词
冠心病
红细胞流变性
血脂
病理
载脂蛋白
coronary heart disease erythrocyte rhedogial properties blood Lipid
