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航海训练对机体干扰素-γ和淋巴细胞增殖活性的影响

Study on the levels of IFN-γ and the proliferation of peripheral-blood lymphocyte of the marine men
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摘要 目的通过检测训练期间航海人员的干扰素-γ和淋巴细胞增值活性,了解航海人员机体免疫力状况。方法选择某部正在从事训练的航海人员24人、后勤人员24人,采集静脉血,检测干扰素-γ(IFN-γ)、淋巴细胞增殖活性、总抗氧化力(T-AOC)、丙二醛(MDA)、白细胞(WBC)及分类等指标。结果航海人员和后勤人员的IFN-γ水平分别是(31.89±0.47)pg/ml和(34.93±0.34)pg/ml;加入H2O2诱导氧化损伤后,航海人员和后勤人员的淋巴细胞增值活性分别为(0.23±0.01)和(0.27±0.01);差异均有显著性意义(P<0.05)。结论与后勤人员相比,航海人员免疫力状况较差。 Objective To investigate the status of immunity ability by examining the levels of IFN-γ and the proliferation of peripheral-blood lymphocyte of the marine men.Methods Twenty four marine men and twenty four logistics men were recruited and blood samples were collected.The levels of IFN-γ,the proliferation of peripheral-blood lymphocyte(PPL),total antioxidant capacity(T-AOC),malondialdehyde(MDA) and white blood cell(WBC) of them were examined.Results The levels of IFN-γ of the marine men and the logistics men were(31.89±0.47)pg/ml and(34.93±0.34)pg/ml respectively,and the proliferation of PPL of them were 0.23±0.01 and 0.27±0.01 respectivly after the H2O2 was added.All of the differences were significant(P0.05).Conclusion The status of immunity ability of the marine men is lower than that of the logistics men.
作者 袁媛 邱霞
机构地区 海军机关门诊部 [
出处 《海军总医院学报》 2011年第1期17-18,24,共3页 Journal of Naval General Hospital of PLA
关键词 干扰素-Γ 淋巴细胞增殖活性 航海人员 IFN-γ Proliferation of peripheral-blood lymphocyte Marine men
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