摘要
目的探讨应用弥可保联合丹参酮ⅡA磺酸钠治疗由外伤等原因所致眼外肌麻痹的临床疗效。方法观察57例（57眼）眼外肌麻痹（排除炎症，肿瘤，重症肌无力，Graves眼眶病，伴有肌肉及组织嵌顿的眶壁骨折），应用弥可保联合丹参酮ⅡA磺酸钠治疗，对比分析以往采用弥可保治疗53例（53眼）眼外肌麻痹者。结果弥可保联合丹参酮ⅡA磺酸钠治疗组有效49例（49眼），总有效率85．96％（49／57）。对由颅脑外伤或眼眶外伤引起眼外肌麻痹总有效率86．96％（20／23）；对由糖尿病、高血压、高血脂、腔隙性脑梗塞等血管性疾病引起眼外肌麻痹总有效率达93．33％（28／30）。弥可保对照组有效28例（28眼），总有效率52．83％（28／53）。两组疗效差异有统计学意义（P〈0．05）。结论弥可保联合丹参酮ⅡA磺酸钠治疗眼外肌麻痹能明显提高治愈率。
Objective To investigate the effect of the combined treatment with Methycobal and Sodium Tanshinone ⅡA Sulfonate in ophthalmoplegia due to trauma. Methods 57 cases （57 eyes）of acquired ophthalmoplegia（ exclusion inflammation, tumor, myasthenia gravis , Graves ophthalmopathy and orbital blowout fractures with muscle and tissue incarceration）were treated with Methycobal and Sodium Tanshinone ⅡA Sulfonate, compared with 53 patients （ 53 eyes ） treated with Methycobal former years. Results In Methyeobal and Sodium Tanshinone ⅡA Sulfonate group, efficacy 49 cases, total effective rate was 85.96%, the total effective rate of treatment of ophthalmoplegia caused by cranioeerebral trauma or orbital trauma, and ophthalmoplegia related with diabetes, hypertension, hyperlipemia and lacunar infarction were 86.96 % and 93.33 % respectively. In Control group, efficacy 28 cases, total effective rate was 52.83% . The results differed significantly between the two groups. Conclusion Treatment with Methycobal and Sodium Tanshinone IIA Sulfonate can increase the cure rate of ophthalmoplegia.
出处
《中华眼外伤职业眼病杂志》
2011年第11期839-842,共4页
Chinese Journal of Ocular Trauma and Occupational Eye Disease
关键词
弥可保
丹参酮ⅡA
眼外肌麻痹
Methycobal
Sodium Tanshinone ⅡA Sulfonate
Ophthalmoplegia
