摘要
纳米混悬剂可增大难溶性药物的溶解度和生物利用度,提高药物的安全性和有效性。纳米混悬剂作为20世纪末发展起来的一种新的给药系统,在药物中的应用受到广泛关注。本文对纳米混悬剂的制备方法、原理、应用现状进行了阐述,列举了其在药物制剂中的研究应用,并对其优势、存在的问题进行了分析和展望。
Nanosuspension technology can be used to enhance the solubility and bioavailability of poorly soluble drugs,and improve drug safety and efficiency.Nanosuspension as a new drug delivery system was developed in the end of 20th,it has become a useful formulation in drugs.This paper discusses the method of preparations,principle and application perspectives of the method,its application drugs and possible problems working with nanosuspension.
出处
《药学与临床研究》
2011年第5期439-442,共4页
Pharmaceutical and Clinical Research
基金
澳门科学技术发展基金(No.003/2011/A)
关键词
纳米混悬剂
难溶性药物
应用
Nanosuspension
Poorly soluble drugs
Application
