摘要
目的研究棠梨花的化学成分。方法采用硅胶柱层析,凝胶Pharmadex LH-20柱层析进行分离,采用光谱分析方法包括MS和1D-NMR鉴定化合物结构。结果从棠梨花中分离得到了13个化合物,分别鉴定为熊果醇(1),熊果醛(2),对羟基苄基甲基醚(3),对羟基苄基乙基醚(4),E-1-(4'-羟基苯基)-丁-1-烯-3-酮(5),5,6α-环氧-3β-醇-豆甾烷(6),5,6β-环氧-3β-醇-豆甾烷(7),豆甾-5-烯-3β,7α-二醇(8),棕榈酸胡萝卜苷(9),1,3-二亚油酸甘油酯(10),亚油酸(11),胡萝卜苷(12),β-谷甾醇(13)。结论化合物1～11首次从川梨中分离得到。
ObjectiveTo study the chemical constituents of the flowers of Pyrus pashia Buch.-Ham.ex D.Don. MethodsCompounds were isolated and purified by silica gel and Sephadex LH-20 column chromatography.Their chemical structures were identified on the basis of spectral data. ResultsThirteen compounds were isolated and identified as： uvaol（1）,ursolic aldehyde（2）,4-hydroxybenzyl methyl ether（3）,4-hydroxybenzyl ethyl ether（4）,E-1-（4′-hydroxyphenyl）-but-1-ene-3-one（5）,5,6β-epoxy-5β-sitostan-3β-ol（6）,5,6α-epoxy-5α-sitostan-3β-ol（7）,stigmasta-5-en-3β,7α-diol（8）,daucosterol plamitate（9）,glycerol 1,3-di-（9Z,12Z-octadecadienoate）（10）,linoleic acid（11）,daucosterol（12）,β-sitoterol（13）. ConclusionCompounds 1-11 were isolated from this plant for the first time.
出处
《时珍国医国药》
CAS
CSCD
北大核心
2011年第10期2373-2375,共3页
Lishizhen Medicine and Materia Medica Research
基金
云南省自然科学基金(2010CD017)
云南省大学生创新性实验计划项目
关键词
棠梨
花
三萜
甾醇
Pyrus pashia Buch.-Ham.ex D.Don
Flowers
Triterpene
Sterol
