摘要
目的:探讨鼻咽癌治疗后颈淋巴结残留或复发的手术治疗的疗效。方法:回顾性分析我院57例因鼻咽癌放疗后颈淋巴结残留或复发行颈清扫术的患者,应用Kaplan-Meier法进行生存率分析,采用COX回归模型对影响生存率的相关因素进行分析。结果:术后1﹑3﹑5年生存率分别为82.1%﹑54.8%﹑34.7%。多因素分析表明,放疗后至手术之日的间隔时间超过24个月,复发或残留淋巴结再分期较晚,淋巴结外侵犯预后差。结论:颈淋巴结清扫术为治疗鼻咽癌放射治疗后颈淋巴结残留或复发的有效方法,可以提高患者的生存率。
Objective： To explore the effect of radical neck dissection performing of patients with nasopharyngeal carcinoma who had persistent or recurrent cervical lymph nodes after radiotherapy. Methods： 57 patients with lymph node persistence or recurrent after radiotherapy receiving radical neck dissection were analyzed retrospectively. The cumulative survival rate was analyzed by a Kaplan-Meier method. The Influencing factors were screened by COX proportional hazards model. Results： The 1-year, 3-year and 5-year overall survival rates were 82.1%, 54.8%, 34.7%, respectively; multivariate analysis showed that significant factors influencing survival included interval between completion of radiotherapy and surgery, the outside tissues of lymph node involved or not, and rN stage. Conclusion： Radical neck dissection can improve survival rate of patients with nasopharyngeal carcinoma who have persistent or recurrent cervical lymph nodes after radiotherapy.
出处
《中国医药导报》
CAS
2011年第32期183-185,共3页
China Medical Herald
关键词
鼻咽癌
颈淋巴结清扫术
残留
复发
放射治疗
Nasopharyngeal carcinoma
Radical neck dissection
Persistent
Recurrence
Radiotherapy
