摘要
目的探讨哮喘病情与肺功能指标变化特点,为哮喘规范化治疗提供客观依据。方法采用肺功能测定系统对25例哮喘患儿于急性期、缓解期6个月及1年分别行常规肺通气功能测定,比较各期实测值与预计值比值之间的差异。结果哮喘患儿的症状与肺功能指标呈现出一致性,急性期大气道指标用力肺活量(FVC)、1秒钟用力呼气量(FEV1)、最大呼气峰流量(PEF)及75%、50%、25%肺活量时用力呼气流速(FEF25、50、75)、中段呼气流速(MMEF75/25)等实测值与预计值比值均降低,治疗6个月后FVC、FEV1等大气道功能指标基本恢复,1年后小气道功能指标FEF50、75及MMEF75/25等指标恢复。结论肺功能指标在哮喘的病情评估方面具有重要作用,对于哮喘治疗具有重要指导作用。
Objective To analyse the differences of pulmonary function indexes before and after standard treatment in asthmatic children,to explore the clinical characteristic of asthma,for providing an objective basis for standardized treatment of asthma.Methods Twenty-five asthmatic children were recruited.The pulmonary function tests were performed by spirometry in asthma attack and in remission for 6 months and one year.The measured values were compared with the expected values in different periods.Results The symptoms were consistent with lung function indexes in asthmatic children.During an asthma attack,the measured values of forced vital capacity（FVC）,forced expiratory volume in one second（FEV1）,peak expiratory flow（PEF）,forced expiratory flow at 75%,50%,25% vital capacity（FEF 25,50,75）,and maximum midexpiratory flow（MMEF 75/25）were lower than expected values.After remission for 6 months,the measured values of FVC and FEV1 recovered.After remission for 1 year or more,the small airway function indexes,FEF50,FEF 75,MMEF 75/25,recovered.Conclusions Lung functional indexes have an important role in assessment of asthma and they are also an important guide for asthma treatment.
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2011年第10期977-979,共3页
Journal of Clinical Pediatrics
基金
河北省医学适用技术跟踪项目(No.GL200841)
关键词
哮喘
肺功能
儿童
asthma
lung function
child
