摘要
目的:探讨125I放射性粒子植入治疗非小细胞肺癌(NSCLC)伴肺不张中PET-CT对肿瘤靶区定位的价值。方法:2006年5月~2009年12月随机选择26例晚期NSCLC合并肺不张患者植入前分别行PET-CT检查,将PET-CT及与其对应的CT图像分别输入计划系统(Treatment plan system,TPS)进行放射治疗剂量计算,将所得靶区体积(Gross tumor volume,GTV)及计划粒子数进行比较。然后做CT引导下经皮穿刺125I粒子植入治疗。结果:PET-CT组和CT组肺癌GTV分别为(51.03±16.02)cm3,(58.10±19.11)cm3,两组应植入粒子数分别为43.88±12.30个和49.46±14.74个,PET-CT组GTV较CT组GTV体积减少12.17%,植入粒子数减少11.28%(P<0.001)。结论:应用PET-CT在NSCLC 125I放射性粒子植入治疗术前肿瘤靶区定位方面较CT更加准确。
Objective： To explore the location value of PET-CT in 125I seeds permanent braehytherapy treatment for non-small cell lung carcinoma（NSCLC） patients.Methods： From 26 patients with NSCLC underwent whole body PET-CT scans,PET-CT and CT images were input into the treatment plan system（TPS）,radiotheapy dose were calculated,compared with gross tumor volume and the numbers of 125I seeds.Results： The gross tumor volume,the mean number of seeds were（51.03±16.02）cm3,43.88±12.30,in PET-CT group and（58.10±19.11）cm3,49.46±14.74 respectively,in CT group,gross tumor volume of PET-CT group reduced 12.17%,number of seeds reduced 11.28%（P0.001）.Conclusion： PET-CT is more accurate than CT alone in the assessment of the radiation target volume for NSCLC patients.
出处
《中国临床医学影像杂志》
CAS
北大核心
2011年第9期616-618,共3页
Journal of China Clinic Medical Imaging
