摘要
目的:利用Meta分析方法评价丹参酮Ⅱ_A注射液治疗脑梗死的疗效和安全性。方法:检索国内、外公开发表的关于丹参酮Ⅱ_A注射液治疗急性脑梗死临床试验文献,利用RevMan 4.2软件对纳入文献进行Meta分析。结果:采用固定效应模型对10个研究做Meta分析,丹参酮Ⅱ_A注射液治疗脑梗死的有效性与对照组比较,差异有统计学意义;丹参酮Ⅱ_A注射液治疗脑梗死的不良反应与对照组比较,差异无统计学意义。结论:丹参酮Ⅱ_A注射液治疗脑梗死安全、有效。
Objective： To evaluate the curative effect and safety of tanshinone Ⅱ A injection in the treatment of acute cerebral infarction （ACI） with Meta analysis. Method： The related literatures concerning clinical trims on tanshinone Ⅱ A injection in the treatment of ACI published at home and abroad were retrieved, and Meta analysis was conducted on the selected literatures by Review Manager 4. 2 software. Result： Changeless benefit model 10 research findings statistics and analysis showed that the curative effect of tanshinone Ⅱ A injection for acute cerebral infarction in the treatment group had a significant difference compared with that in the control group and the ADR ＇in the treatment group had no significant difference. Conclusion： The existing clinical evidences show that tanshinone Ⅱ A injection is safe and effective in the treatment of ACI.
出处
《中国药师》
CAS
2011年第10期1481-1483,共3页
China Pharmacist
关键词
丹参酮ⅡA注射液
脑梗死
META分析
Tanshinone Ⅱ A injection
Acute cerebral infarction
Meta-analysis
