摘要
目的探讨1.5 TMR扫描仪上IFIR序列评估肝硬化门脉系统改变的可行性及临床意义。方法对40例肝硬化患者组成的肝硬化组和20例健康志愿者组成的对照组通过三种不同的饱合带预加方式进行三次冠状位IFIR序列扫描。在ADW4.4工作站上行MIP重建,对门静脉各级分支显示程度及清晰度进行评分;测量肝硬化患者PV、SV、SMV内径宽度及脾脏体积,并与对照组比较,再按Child-Pugh肝功能分级将肝硬化患者分为A级、B级、C级三组,进行组间对比分析;观察侧支循环的有无,并评估其与脾脏体积大小的关系。结果 40例肝硬化患者中,3例脾切除患者及3例门脉系统血栓患者出组,34例入组肝硬化患者中25例(74%)为高分组(3～4分);9例(26%)为低分组(1～2分)。肝硬化患者PV、SV内径及脾脏体积比健康对照组明显增大(P<0.05);随肝硬化程度加重,PV内径逐渐减小(P<0.05),SV、SMV内径逐渐增大,脾脏体积逐渐增大(P>0.05)。34名患者中22例(65%)侧支循环建立,有侧支循环建立者较无侧枝循环者脾脏体积略增大(P>0.05)。结论1.5T磁共振IFIR序列无需造影增强便能够清晰显示门脉系统,测量肝硬化患者门静脉系统各管径宽度及脾脏体积,观察侧支循环的有无,为评估肝硬化门脉血流动力学改变提供可行的检测手段,为预测肝硬化门脉高压时脾切除的临床意义提供可靠依据。
Objective： To study the feasibility and clinical significance of IFIR sequence in portal system changes after hepatic cirrhosis on 1.5 T MR. Materials and Methods： Forty patients with hepatic cirrhosis and 20 normal volunteers （control group） were scanned on GE signa 1.5 T HD echospeed MRI with 3 types of presaturation band. MIP reconstruction was done on ADW 4.4 workstation to evaluate the branches and trunk of portal vein; measure the diameters of portal vein （PV）, splenic vein （SV）, superior mesenteric vein （SMV） and splenic volume, and those data were compared with control group. The data were also compared with different graded patients （A, B, C grade） with the grading of Child-Pugh; and the collateral circulation （CC） to assess the relationship with the splenic volume were observed. Results： In the 40 cases of hepatic cirrhosis patients, 6 cases were out of group （3 cases in splenectomy, 3 in portal system thrombosis）. Among 34 patients, 25 cases （74%, 25/34） belong to high grade （3-4 grade） and 9 cases （26%, 9/34） were low grade （1-2 grade）. The diameters of PV, SV, SMV and splenic volume in patients group were significantly larger than those in controls （P〈0.05）. The PV diameter showed a descent tendency （P〈0.05） with the damage of liver function, while the diameter of SV, SMV and splenic volume showed an increased tendency （P〈0.05）. Among 34 patients, 22 cases （65%） were present of collateral circulation, and the splenic volume among those was larger than that of patients in no-CC groups （P〈0.05）. Conclusion： It is feasible to show the branches and main trunk of portal vein and assess the hemodynamics of portal vein system using IFIR sequence without contrast media on 1.5 T MRI.
出处
《磁共振成像》
CAS
2011年第5期358-362,共5页
Chinese Journal of Magnetic Resonance Imaging
关键词
肝硬化
门静脉系统
插入有限脉冲响应
磁共振成像
Cirrhosis
Portal venous system
Interpolated finite impulse response
Magnetic resonance imaging
