摘要
目的:比较银杏磷脂胶囊与血脂康胶囊治疗高脂血症的临床疗效。方法:将60例高脂血症患者随机分为2组,分别服用血脂康胶囊和银杏磷脂胶囊。进行治疗前后对体重指数、总胆固醇、三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、脂蛋白(a)、C反应蛋白与纤维蛋白原比较。结果:与治疗前比较,2种药物均能明显降低总胆固醇、三酰甘油、低密度脂蛋白胆固醇、升高高密度脂蛋白胆固醇(P<0.05)、C反应蛋白与纤维蛋白原(P<0.01);与对照组比较,治疗组患者的脂蛋白(a)明显降低(P<0.05)。结论:银杏磷脂胶囊有调节血脂的作用,且降低脂蛋白(a)与纤维蛋白原的作用较血脂康强。
OBJECTIVE To compare the clinical effects of Ginkgo biloba phosphatide capsule and Xuezhikang capsule on treatment of hyperlipemia. METHODS 60 cases of patients with hyperlipemia were randomly divided into two groups, and the two groups took the Xuezhikang capsule and Ginkgo biloba phosphatide capsule group, and then the weight index, total cholesterol, triglyeeride, high density lipoprotein cholesterol, low density lipoprotein cholesterol, lipoprotein (a), C reactive protein and fibrinogen content of two groups were compared before and after treatment. RESULTS Comparing with before treatment two groups showed, the effects on reducing the total cholesterol, triglyceride low density lipoprotein cholesterol, boosting the high density lipoprotein cholesterol were observed (P〈0. 05), and on decreasing the C reactive protein and fibrinogen of the both groups were seen as well(P〈0. 01 ) after treatment. Comparing with Xuezhikang capsule group, Ginkgo biloba phospha- tide capsule had the effect on lowering lipoprotein (a) (P〈0. 05). CONCLUSION Ginkgo biloba phosphatide capsule has the better effects on regulating the blood lipid, and on reducing the lipoprotein (a) and fibrinogen than Xuezhikang capsule.
出处
《中国医院药学杂志》
CAS
CSCD
北大核心
2011年第19期1613-1615,共3页
Chinese Journal of Hospital Pharmacy
基金
武汉市卫生局临床医学科研项目(中医药及中西医结合类)[编号:武卫(2009)76号]
关键词
银杏磷脂胶囊
高脂血症
疗效
Ginkgo biloba phosphatide capsule
hyperlipemia
effect