摘要
目的:探讨≤55岁中青年冠心病患者危险因素及经皮冠脉介入治疗(PC I)特点。方法:根据患者年龄分为中青年组(≤55岁,152例)和老年组(≥75岁,109例),比较2组间发病的危险因素、PC I治疗特点及术后严重并发症情况,评价2组间PC I治疗疗效。结果:中青年组冠心病患者中男性、有阳性家族史、吸烟、高脂血症者明显多于老年组(P<0.01),老年组冠心病患者原发性高血压、糖尿病检出率高于中青年组(P<0.01)。冠脉造影结果显示:中青年组患者以单支病变为主,且多为局限性狭窄,明显多于老年组(P<0.01);老年组患者三支血管病变、弥漫性狭窄病变、钙化病变明显多于中青年组(P<0.01);双支血管病变2组间无统计学意义。2组间支架置入情况相比,中青年患者右冠状动脉支架置入数少于老年组(P<0.05),差异有统计学意义。2组患者手术成功率及严重并发症(P>0.05)差异无统计学意义。结论:吸烟、高脂血症、冠心病家族史是中青年冠心病发病的重要危险因素。中青年冠心病患者冠状动脉以单支血管病变居多,三支血管病变少见,弥漫性狭窄、钙化病变亦少见。中青年组冠心病患者右冠状动脉支架置入数少于老年组。
Objective：To analyse the risk factors and characteristics of percutaneous coronary intervention（PCI） therapy of young-middle-aged patients with coronary artery disease（CAD）.Methods：The risk factors,characteristics of PCI and severe complication of 152 young-middle-aged CAD patients（≤55 y） and 109 old aged CAD patients（≥75 y） were collected,analysed and compared.Results：The rates of male,family history,smoking and hyperlipemia were significantly higher in young-middle-aged CAD patients than those in old-aged（P0.01）,and the rates of hypertension and diabetes mellitus were significantly lower（P0.01）.Coronary angiography illustrated that single-vessle lesions more occured in young-middle-aged group than old-aged group;Three-vessle,diffuse and calcifeid lesions occured more in old-aged group.There were no significant difference in two-vessle lesions between two groups.Stents embedded in right coronary artery were significantly less in young-middle-aged group than those in old-aged group（P0.01）.There were no significant difference in rate of success and severe complication between two groups.Conclusions：smoking,hyperlipemia and family history are important risk factors in young-middle-aged patients with CAD.Single-vessle lesions occured more in young-middle-aged group,but three-vessle,diffuse and calcifeid lesions occured less.Stents embedded in right coronary artery were significantly less in young-middle-aged group than those in old-aged group.
出处
《赣南医学院学报》
2011年第4期545-547,共3页
JOURNAL OF GANNAN MEDICAL UNIVERSITY
关键词
中青年冠心病
危险因素
经皮冠状动脉介入治疗
young-middle-aged patients with coronary artery disease
risk factors
percutaneous coronary intervention
