摘要
目的探讨原发性肺副节瘤的临床病理特征和生物学行为。方法对1例原发性肺副节瘤进行组织学观察和免疫组化标记分析，同时复习相关文献。结果原发性肺副节瘤的组织学改变类似于其他部位的副神经节瘤。免疫组化标记：瘤细胞Syn、NSE、Cg,A、S-100、GFAP均阳性，CK、EMA、CEA、HMB-45、CD34、CD68和CD99均阴性。结论副节瘤是一种起源于副神经节的肿瘤，较少见。而原发性肺副节瘤极为罕见。呈侵袭性生长，有低度恶性的生物学行为。根据肿瘤的组织学特征和免疫组化表达，结合临床资料及影象学检查可以作出诊断。
Objective To investigate glomus juglare tumor＇ s clinical features of pathology, and to analyze its biological behavior. Methods A case of glomus jugulare tumor was analyzed referring to the relevant literatures. Results Primary glomus jugulare tumor appeared similar to that of paraganglioma in the other part of human body. Immunohistochemical staining for Syn, S-100, CgA and NSE, GFAP was positive and negative for CK, EMA, CEA, HMB-45, CD34 and CD99 in the tumor ceils. Conclusion Glomus jugulare tumor is a rare neoplasm arising from the paraganglion and it purses an aggressive ability and lower grade in biological behavior. Analyzing histological features combining with data reference of CT or MRI and immunohistochemical staining, the pathological diagnosis of glomus jugulare tumor can be made.
出处
《中国急救复苏与灾害医学杂志》
2011年第9期775-777,785,共4页
China Journal of Emergency Resuscitation and Disaster Medicine
关键词
肺
副节瘤
免疫组织化学
Paraganglioma
Glomus jugulare tumor
Immunohistochemistry
