摘要
骨桥蛋白是一种带负电荷、具有亲水性的分泌型磷酸化糖蛋白,由多种组织细胞合成与分泌,存在于体内多种组织和细胞中。该蛋白结构上与多种基质蛋白相似,功能上具有细胞因子的特点,参与了机体多种病理过程。近年来的研究证实,骨桥蛋白在肝棘球蚴的外囊中大量表达,并在其形成过程中起重要作用。
Osteopontin is a negatively charged, hydrophilic secreted phosphorylated glycoprotein. It is synthesized and secreted by a variety of cells, and is found in various tissues and ceils. The protein is similar in structure to matrix proteins, has the characteristics of cytokines in function and invovled in a series of pathological processes. Recent studies confirmed that osteopontin is highly expressed in liver hydatid cyst and may play an important role in cyst formation.
出处
《中国寄生虫学与寄生虫病杂志》
CAS
CSCD
北大核心
2011年第4期310-313,318,共5页
Chinese Journal of Parasitology and Parasitic Diseases
基金
国家自然科学基金(No30860274)~~
