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埃兹蛋白与肿瘤转移关系的研究进展 被引量:2

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摘要 转移是恶性肿瘤的主要生物学特征,是导致肿瘤患者死亡的主要原因。关于肿瘤的发生机制的研究已取得重大突破,但对于肿瘤细胞转移的具体机制仍不甚清楚。这篇综述的目的是提供一个已被证实参与肿瘤发生、转移的分子:埃兹(Ezrin)蛋白,作为埃兹蛋白/根蛋白/膜突蛋白(ezrin/radixin/moesin,ERM)蛋白家族的成员之一,是一种细胞膜与细胞骨架的连接蛋白,是将细胞外信号传递到骨架蛋白的重要联系分子,参与细胞黏附和运动,并参与细胞凋亡和吞噬。
作者 张庆飞 杨兵
出处 《临床医药实践》 2011年第9期684-686,共3页 Proceeding of Clinical Medicine
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