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颅内动脉瘤合并心肌损伤的临床研究 被引量:3

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摘要 目的:总结颅内动脉瘤并心肌损伤患者临床特点,探讨心肌损伤机制。方法:125例颅内动脉瘤患者,动态观察心电图变化,测定血浆肌钙蛋白I(cTnI)及脑型利钠肽水平(BNP),心脏彩色多普勒超声评价心室壁运动及心功能状态,分析心肌损伤与动脉瘤出血部位及神经功能缺失Hunt分级关系。结果:38例患者合并心肌损伤,24例心电图有心律失常、心肌缺血;所有心肌损伤患者3d内血浆肌钙蛋白I及脑型利钠肽明显升高(cTnI 3.12±0.89、BNP13410.26±57.94),28例患者心脏超声显示室间隔、左室心尖运动低平,左室射血分数(45.91±2.04%)低于正常患者,心腔扩大不明显。3d后心电图、影像学及心肌损伤标志物开始恢复。心肌损伤与Hunt分级关系密切,与动脉瘤部位无关。结论:颅内动脉瘤易合并心肌损伤,呈可逆性特点,与神经功能缺失密切相关,机制可能与神经源性心肌顿抑有关。
出处 《陕西医学杂志》 CAS 2011年第8期962-964,共3页 Shaanxi Medical Journal
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