摘要
目的探讨甲氨蝶呤联合米非司酮治疗异位妊娠的疗效。方法收集我院2008年9月～2010年3月未破裂输卵管妊娠患者62例,随机分为观察组和对照组各31例。观察组给予甲氨蝶呤和米非司酮联合治疗,对照组给予甲氨蝶呤治疗。观察两组治愈率、治疗前后盆腔包块大小、血β-HCG变化及不良反应发生情况。结果观察组的治愈率明显高于对照组,两者比较差异有统计学意义(P<0.05);观察组和对照组治疗后血β-HCG均较治疗前显著降低,但观察组降低幅度大于对照组(P<0.05);盆腔包块大小治疗后两组无显著性差异(P>0.05);两组患者不良反应发生率差异无统计学意义。结论甲氨蝶呤联合米非司酮保守治疗异位妊娠效果较好,值得临床推广。
Objective To explore the effect of methotrexate combined with mifepristone on ectopic pregnancy. Methods 62 cases of non-reptured tubal preghancy were select from Sep 2008 to Mar 2010 in our hospital, they were randomly divided into control group and observation group, each having 31 cases. Observation group was treated with methotrexate and mifepristone, but the control group was treated with methotrexate only, the cure rate, β -HCC of blood, the size of the adnexal mass of before and after treatment and adverse effect were observed after treatment. Results The cure rate of observation group was higher than that of control group, there was a significant difference （P 〈 0.05 ） ; β -HCG of blood in two group after treatment were much lower than before treatment, the reduction of the treatment group was larger than control group （ P 〈 0.05 ）; There were no significant difference in the adnexal mass and the rate of adverse effect between two groups after treatment （ P 〉 0.05 ）. Conclusion The effect of methotrexate combined with mifepristone on ectopic pregnancy is good, this method is worthy of application.
出处
《中国现代医生》
2011年第22期66-67,共2页
China Modern Doctor
