摘要
目的观察丹参酮ⅡA磺酸钠联合激素治疗肾病综合征的临床疗效。方法将48例肾病综合征患者随机分为两组,各24例。对照组采用足量强的松及常规治疗。治疗组在足量强的松及常规治疗基础上加用丹参酮ⅡA磺酸钠注射液静脉滴注,两组疗程均为2周。分别观察两组治疗前后尿常规、24h尿蛋白定量、血脂等指标变化。结果治疗后两组患者24h尿蛋白定量较治疗前均明显降低,治疗组总有效率为90.7%,对照组为78.0%(P<0.05)。治疗组治疗后血脂、肾功能等指标较治疗前均有显著改善,与对照组比较差异有统计学意义(P<0.05)。结论丹参酮ⅡA磺酸钠注射液联合激素能显著提高治疗肾病综合征的疗效。
Objective To discuss the efficacy of Sulfontanshinone ⅡA Sodium Injection combined with prednisone for primary nephrotic syndrome. Methods 48 patients with PNS were randomized into two groups.24 patients in control group were treated with full dosage of prednisone and conventional therapy,24 patients in treatment group received full dosage of prednisone,conventional therapy and intravenous＂ Sulfontanshinone ⅡA Sodium ＂. Rennal function,blood fat and 24-hour urine protein were detected. Results 24-hour urine protein in patients of both groups were all decreased;total effective rate was 90.7%in treatment group and 78% in control group. As compared with control group,blood fat and renal function in treatment group were improved significantly（P 0.05）.Conclusion Sulfontanshinone ⅡA Sodium Injection combined with prednisone may improve PNS.
出处
《中国医药科学》
2011年第15期12-13,共2页
China Medicine And Pharmacy
关键词
丹参酮ⅡA磺酸钠
肾病综合征
强的松
Sulfontanshinone ⅡA Sodium
Primary nephrotic syndrome
Prednisone
