摘要
目的改进氢化可的松乳膏现有质量标准的含量测定方法。方法通过改进供试品的提取处理过程,优化操作步骤。结果改进方法的氢化可的松平均回收率为98.57%,RSD=1.17%(n=9),测定结果与药典方法结果比较没有明显差别,可代替原提取方法。结论该方法准确度高、操作简便,适用于医院制剂的快速检验。
Objective To improve the current method for determining the content o f Hydrocortisone Cream.Methods The extracting process of sample was improved in order to reduce the procedure.Results The average recovery rate of hydrocortison e was 98.57%with RSD of 1.17%.There was no significant difference in the conte nt between the two determination methods.The current method can be replaced by t he new method.Conclusion The method is simple,accurate.It is suitable for the r apid analysis of this hospital preparation.
出处
《中国药业》
CAS
2011年第15期25-25,共1页
China Pharmaceuticals
关键词
氢化可的松乳膏
含量测定
方法改进
Hydrocortisone Cream
content determination
method improvement