摘要
目的:探讨肤乐霜治疗婴幼儿湿疹和特应性皮炎的效果有效性,并观察其安全性。方法:选取什么医院什么时间段婴幼儿湿疹和特应性皮炎患儿71例,给予肤乐霜均匀涂于患处,2次/d。在治疗前后分别对红斑、水肿/浸润/丘疹、抓痕、渗出/结痂、鳞屑/干皮征、苔藓样变的积分进行评价并记录不良事件。结果:肤乐霜治疗湿疹和特应性皮炎的总显效率为62%,其中急性湿疹为68.2%,亚急性湿疹为62.5%,慢性湿疹为53.3%,特应性皮炎为61.1%。婴幼儿湿疹和特应性皮炎总显效率差异无统计学意义;治疗后的SCORDA评分均较治疗前有显著降低(P<0.01);不良反应均为一过性,未影响治疗。结论:肤乐霜对婴幼儿湿疹和特应性皮炎均有良好疗效,安全性高,值得临床推广应用。
Objective： To evaluate the efficacy and safety of rule cream for the theatment of infantile eczema and atopic dermatitis. Method： Fule cream was used twice a day in 71 children with eczema and atopic dermatitis. These symptom scores of erythema, edema/infiltration/papules, scratches, oozing/crusting, scaling/ dry skin syndrome and lichenification were compared before and after the treatment. At the same time, the adverse events were recorded. Result： The total effective rate of the treatment in infantile eczema and atopic dermatitis was 62%. The effective rate in the children with acute eczema, subacute eczema, chronic eczema and atopie dermatitis were 68.2% , 62.5% , 53.3% and 61.1% , respectively. The difference for total effective rate among the four groups was not significant among three groups. SCORDA scores after the treatment were significantly lower than that before the treatment （P 〈 O. 01 ）. Adverse reactions were transient, which had no impacts on the treatment. Conclusion： Fule cream have a promising efficacy for the treatment of infantile eczema and atopic dermatitis with a high safety.
出处
《中国实验方剂学杂志》
CAS
北大核心
2014年第12期238-240,共3页
Chinese Journal of Experimental Traditional Medical Formulae
基金
北京市科委基金项目(Z121100000312005)
关键词
肤乐霜
婴幼儿湿疹
特应性皮炎
Fule cream
infantile eczema
atopic dermatitis
