摘要
目的观察培朵普利联合比索洛尔治疗慢性充血性心衰的临床疗效。方法选2008年至2010年105例住院慢性充血性心衰患者随机分为培朵普利治疗组(n=56)和在培朵普利片基础上逐渐加量比索洛尔至最大耐受量对照组(n=49)。观察一年后两组左室舒张末期内径、左室收缩末期内径、左室射血分数(LVEF);心功能分级、6 min步行实验。结果一年后培朵普利联合比索洛尔组在临床症状有显著的效果(P<0.01);心功能分级;6 min步行距离、左室舒张末和收缩末内径、LVEF等方面较单独培朵普利组有优越性(P<0.01)。结论培朵普利联合比索洛尔较单独培朵普利治疗慢性充血性心衰有更优越的临床疗效。
Objective To observe the effect of Perindopril combined with Bisoprdol on congestive heart failure.Methods From 2008 to 2010,100 cases of chronic congestive heart failure in patients were randomly divided into treatment group DORA buildup Pulitzer（n = 56）and at which based on the Pulitzer piece duo gradually added amount bisoprolol to maximum tolerance group（n = 49）.Observed a year later two groups of left ventricular end-diastolic inner diameter and left ventricular end-systolic inner diameter and left ventricular ejection fraction（LVEF）,cardiac grading,6 minutes walking experiments.Results after a year Canberra Pulitzer macchiato joint bisoprolol group in the clinical symptoms were remarkable effect（P〈0.01）cardiac classification;6 minutes walking distance,left ventricular end-diastolic and contraction diameter,at the end of a separate aspects LVEF liangyoupeijiu Pulitzer groups had advantages of DORA（P〈0.01）.Conclusion Perindopril combined with Bisoprolol treatment of CHF is better than Perindoprit.
出处
《中国实用医药》
2011年第20期28-29,共2页
China Practical Medicine
