摘要
以红霉素为模板分子、甲基丙烯酸为功能单体、乙二醇二甲基丙烯酸酯为交联剂,采用沉淀聚合法制备了粒径均一的红霉素纳米分子印迹聚合物微球,优化了分子印迹聚合物的合成条件,确定了模板分子与功能单体的最佳摩尔比为1:3,对其进行了表征.结果表明,所制聚合物对红霉素的实际最大吸附量可达202.12mg/g,吸附约200min达到平衡,对红霉素具有良好的选择性吸附能力.
Uniform molecularly imprinted polymer （MIP） nanoparticles for erythromycin （EM） were prepared by precipitation polymerization using EM as template molecule, methacrylic acid （MAA） as functional monomer and ethylene glycol dimethacrylate （EGDMA） as cross-linker. The synthesis conditions of MIP nanoparticles were optimized and the optimum molar ratio of template molecule to functional monomer was obtained as 1：3. The MIP nanoparticles were characterized. Moreover, the actual maximum apparent adsorption capacity of MIP nanoparticles obtained from the binding experiments was 202.12 mg/g, the adsorption kinetics of MIP nanoparticles showed that the adsorption of MIP nanoparticles in adsorption solution would be equilibrium after 200 min. The MIP nanoparticles for EM possessed highly selective adsorption capacity.
出处
《过程工程学报》
CAS
CSCD
北大核心
2011年第3期481-486,共6页
The Chinese Journal of Process Engineering
基金
国家自然科学基金资助项目(编号:20976179
20506026)
国家高技术研究发展计划(863)基金资助项目(编号:2006AA10Z437)
北京市自然科学基金资助项目(编号:2092027)
关键词
分子印迹聚合物
红霉素
纳米颗粒
沉淀聚合
甲基丙烯酸
乙二醇二甲基丙烯酸酯
molecularly imprinted polymer
erythromycin
nanoparticle
precipitation polymerization
methacrylic acid
ethylene glycol dimethacrylate
