摘要
目的 了解对病程超过3周的突发性聋患者以糖皮质激素等药物进行治疗的意义.方法 对北京大学人民医院耳鼻咽喉科2002年11月至2010年7月住院治疗的48例（58耳）病程超过3周的突发性聋患者的临床资料进行同顾性分析.根据本次入院治疗前的听力曲线分为3组,分别采用不同的治疗方案,观察其疗效.以SPSS 17.0统计软件对数据进行分析,患者治疗前后纯音测听阈值采用t检验.结果 低频下降型（6耳）、高频下降型（22耳）、全频下降型（30耳）治疗后有效率分别为83.3%、31.8%、36.7%.病程≥1年的共12耳,其治疗有效率58.3%（7耳）.全频下降型中本次治疗前气导听阈均值≥90 dB（听力级）的9耳,7耳（77.8%）治疗有效,其中3耳（33.3%）达到显效标准;本次治疗前气导听阈均值＜90 dB的患者21耳,其中3耳（14.3%）治疗有效.结论 病程超过3周的突发性聋患者仍有积极治疗的意义.其中低频下降型治疗有效率最高,高频下降型有效率最低,全频下降型有效率居中.病程≥1年的突发性聋患者经积极治疗仍有改善听力可能.全频下降型、听功能损失程度较重的患者,通过积极治疗获益较大.
Objective To investigate and analyze the significance of a course of glucocortieosteroids and other drugs for the treatment of patients with sudden deafness present for at least three weeks.Methods A retrospective review was done on 48 patients （58 ears） with sudden deafness present for at least three weeks or more,who were admitted to the Department of Otorhinolaryngology,Peking University People＇s Hospital from November 2002 to July 2010.The patients were devided into three groups by the type of hearing threshold.The different treatments were used in the three groups.The SPSS 17.0 software was used to analyze the data.Results In patients with a low tone hearing loss （6 ears） ,83.3% improved.For patients with a high tone loss （22 ears） 31.8% improved.For a flat tone hearing loss （30 ears） 36.7% improved.For patients with a hearing loss more than one year （12 ears） there was improvement in 58.3% （7 ears）of the patients.In 9 ears which had a flat tone hearing loss of 90 dB or greater before treatment,77.8% （7 ears） improved with 33.3% （3 ears） having a significant improvement.In 21 ears which had a hearing threshold was under 90 dB,14.3% （3 ears） improved.Conclusions In the treatment of patients with sudden deafness which was longer than 21 days the treatment was significant,especially for those who had a 90 dB or greater flat-tone type hearing threshold before treatment.Even though the hearing loss was more than a year in some patients there was still a benefit from treatment.
出处
《中华耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2011年第7期539-542,共4页
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
关键词
听觉丧失
突发性
治疗结果
听阈
Hearing loss,sudden
Treatment outcome
Auditory threshold
