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国产奈达铂用于宫颈癌同步放化疗的剂量递增试验 被引量：5

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摘要 目前，同步放化疗已经被认为是局部晚期宫颈癌的一种标准治疗方案。在放疗的基础上加上同步化疗，可以改善高风险宫颈癌患者的疾病无进展生存率和总生存率。奈达铂是一种新型铂类制剂，其有效性高于顺铂，而肾毒性、神经毒性和胃肠道毒性低于顺铂，
作者 朱卫国 于长华 李涛 陈小飞
机构地区 南京医科大学附属淮安第一医院放疗科
出处 《中华肿瘤杂志》 CAS CSCD 北大核心 2011年第7期525-526,共2页 Chinese Journal of Oncology
关键词 宫颈肿瘤 奈达铂 同步放化疗 剂量限制性毒性
分类号 R737.33 [医药卫生—肿瘤]
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参考文献6

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  • 2Monk BJ, Alberts DS, Burger RA, et al. In vitro phase Ⅱ comparison of the cytotoxicity of a novel platinum analog, nedaplatin (254-S) , with that of cisplatin and carboplatin against fresh, human cervical cancers. Gynecol Oncol, 1998, 71:308-312. 被引量：1
  • 3Sasaki Y, Amano T, Mofita M, et al. Phase I study mad pharmacological analysis of cis-diammine ( glycolato ) platinum ( 254-S; NSC 375101D) administered by 5-day continuous intravenous infusion. Cancer Res, 1991, 51:1472-1477. 被引量：1
  • 4Hartmann JT, Lipp HP. Toxicity of platinum compounds. Expert Opin Pharmacother, 2003,4:889-901. 被引量：1
  • 5Koshiyama M, Kinezaki M, Uchida T, et al. Chemosensitivity testing of a novel platinum analog, nedaplatin (254-S), in human gynecological carcinomas: a comparison with eisplatin. Antieancer Res, 2005, 25:4499-4502. 被引量：1
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同被引文献54

  • 1黄建敏,潘莉萍,李冬雪.PET和PET-CT在宫颈癌中的应用价值[J].国际放射医学核医学杂志,2007,31(2):112-114. 被引量：3
  • 2Morris M, Eifel PJ, Lu J, et al. Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer. N Engl J Med, 1999,340 ( 15 ) : 1137-1143. 被引量：1
  • 3Whitney CW, Sause W, Bundy BN, et al. Randomized comparison of fiuorouracil plus cisplatin vs. hydroxyurea as an adjunct to radiation therapy in stage I1 B-IV A carcinoma aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study. J Clin Oncol, 1999,17(5) :1339-1348. 被引量：1
  • 4Peters WA 3rd, Liu PY, Barrett RJ 2n&, et al. Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol, 2000,18 (8) :1606-1613. 被引量：1
  • 5Rose PG, Bundy BN, Watkins EB, et al. Concurrent cisplatin- based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med, 1999,340(15) :1144-1153. 被引量：1
  • 6Keys HM, Bundy BN, Stehman FB, et al. Cisplatin, radiation, and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med, 1999,340(15) :1154-1161. 被引量：1
  • 7Delgado G, Bundy B, Fowler WC Jr, et al. A prospective surgical pathological study of stage I squamous carcinoma of the cervix: a Gynecological Oncology Group study. Gynecol Oncol, 1989,35(3) :314-320. 被引量：1
  • 8Samlal RA, van der Velden J. Early cervical carcinoma: how to manage high-risk patients after radical hysterectomy. Eur J Obstet Gynecol Reprod Biol, 1999,85 (2) : 137-139. 被引量：1
  • 9Lai CH, Hong JH, Hsueh S, et al. Preoperative prognostic variables and the impact of postoperative adjuvant therapy on the outcomes of stage IB or II cervical carcinoma patients with or without pelvic lymph node metastases: an analysis of 891 cases. Cancer, 1999,85 (7) : 1537-1546. 被引量：1
  • 10Schorge JO, Molpus KL, Koelliker D, et al. Stage IB and IIA cervical cancer with negative lymph nodes: the role of adjuvant radiotherapy after radical hysterectomy. Gynecol Oncol, 1997,66 (1) :31-35. 被引量：1

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中华肿瘤杂志
2011年 第7期

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