摘要
目的测定妊高征患者血和新生儿脐血血清中TC、TG、HDL-C、LDL-C和维生素E(VitE)的含量水平并探讨其在妊高征发病中的作用。方法分别用蛋白酶法和比色法测定74例正常孕妇和脐血及69例妊高征(分为妊娠高血压组和轻重度先兆子痫组)孕妇和脐血血清中TC、TG、HDL-C、LDL-C和维生素E(VitE)的含量水平。结果妊娠高血压组、轻重度先兆子痫组较正常孕妇TC、TG和LDL-C含量明显升高(P<0.05,P<0.05),HDL-C和维生素E(VitE)含量则较正常孕妇明显降低(P<0.05,P<0.05),轻重度先兆子痫组与妊娠高血压组间各指标有显著差异(P<0.05)。结论结果提示血脂和维生素E含量的改变对妊高征发生发展起重要作用。
Objective To determine the levels of serum TC、TG、HDL-C、LDL-C and vitamin E（VitE） in the pregnancy-induced hypertension and neonatal cord blood and their roles in the pathogenesis of preeclampsia.Methods The levels of TC、TG、HDL-C、LDL-C were determined by protease method in74normal pregnant women and cord blood and69cases（including pregnancy-induced hypertension mild and severe pre-eclampsia group）of pregnancy induced hypertension and umbilical cord blood,vitamin E（VitE）was determined by Colorimetric method.Results The levels of TC、TG and LDL-C in patients with PIH were increased significantly than those in healthy pregnant women（P0.05,P0.05）and the levels of HDL-C were decreased significantly（P0.05,P0.05）;the difference between PIH and mild and severe PIH is significantly（P0.05）.Conclusion The results suggest that the change of blood lipid and Vitamin（VitE）play an important role on the occurrence and development of PIH.
出处
《中外医疗》
2011年第16期17-18,共2页
China & Foreign Medical Treatment
