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妊娠期高血压疾病的临床流行病学分析 被引量:67

The Clinical Epidemiological Investigation of Patients with Pregnancy-induced Hypertension
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摘要 目的:对妊娠期高血压疾病患者进行临床流行病学调查分析,以了解近年来我院妊娠期高血压疾病的情况。方法:对我院2004年1月至2010年12月收治的523例妊娠期高血压疾病患者的基本情况、母婴并发症、分娩方式、围生儿结局、生化指标等进行回顾性分析。结果:近7年来妊娠期高血压疾病的发病孕周有提前趋势(F=14.79,P<0.01),重度妊娠期高血压疾病的发生率呈上升趋势(#2=91.85,P<0.01),规律产前检查孕妇比例呈上升趋势(#2=34.93,P<0.01),乡村人口所占比例有增加趋势(#2=50.20,P<0.01),分娩方式仍以剖宫产为主(#2=37.06,P<0.01)。新生儿Apgar评分、新生儿体重随妊娠期高血压疾病病情加重有降低趋势(P<0.01)。乳酸脱氢酶、碱性磷酸酶、尿酸指标随病情加重有增高趋势,血钙随病情加重有降低趋势。结论:我院7年来妊娠期高血压疾病有早发、加重的趋势,但母儿不良结局无升高趋势。 Objective:The clinical epidemiological investigation of the patients with pregnancy-induced hy- pertension in the first affiliated hospital of chongqing medical university was done from January 2004 to De- cember 2010, in order to explore the situation of pregnancy-induced hypertension in recent years. Methods: The retrospective analysis of 523 cases of pregnancy-induced hypertension from January 2004 to December 2010 was carried out, including general features, maternal and infant complications,delivery modes, perinatal pregnancy outcomes and biochemical parameters. Results :The gestational weeks of disease onset became earlier( F= 14.79, P 〈0.01 ),the numbers of severe preeclampsia and eclampsia increased markedly(X2 = 91.85, P 〈 0.01 ). Regular antenatal examination bacame more popular (X2 = 34.93, P 〈 0.01 ), and the propotion of rural population became bigger(X2=50.20, P〈O. 01 ). Cesarean section was still the main de- livery mode (X2 =37.06, P〈O. 01 ). Neonatal Apgar score and weight decreased along with the severity of PIH (P 〈0.01 ). The levels of lactic dehydrogenase,alkaline phosphatase and uric acid increased along with the severity of PIH, while blood calcium decreased markedly. Conclutions: Pregnancy-induced hyperten- sion in our hospital showed a tendency of onset earlier and more severe manifestation, while the adverse maternal and neonatal outcomes still maintain a stable level.
出处 《实用妇产科杂志》 CAS CSCD 北大核心 2012年第7期581-585,共5页 Journal of Practical Obstetrics and Gynecology
关键词 妊娠期高血压疾病 流行病学调查 不良结局 Pregnancy-induced hypertension Epidemiology investigation The adverse result of preg-nancy
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