摘要
目的比较苍白密螺旋体或风疹病毒、巨细胞病毒、单纯疱疹病毒(RCH)在孕妇母婴垂直传播概率。方法对近年来医院所有患者中苍白密螺旋体感染情况和4303例进行RCH检测的孕妇进行回顾性分析,并对34例RCH抗体IgM阳性的孕妇和22例孕中晚期苍白密螺旋体阳性孕妇进行经腹脐静脉穿刺后,抽取胎儿血进行检测。结果胎传梅毒感染成逐年上升趋势,而3708例正常孕妇中RCH中一项IgM抗体的47例,阳性率为1.26%,明显低于流产组患者(2.46%)、死胎组(5.26%)及胎儿畸形组(28.54%);在34例RCH IgM抗体阳性的孕妇中,胎儿血中只有1例HSV-IgM呈阳性,随访未发现新生儿异常;在22例梅毒阳性患者中,7例胎儿RPR,TPHA均为阳性;15例胎儿为RPR阴性,TPHA阳性。结论苍白密螺旋体感染比RCH更容易造成宫内感染。
OBJECTIVE To compare mother-infant transmission of syphilis and RCH. METHODS The infections of syphilis and RCH in our hospital were retrospectively analyzed. 34 cases of RCH IgM positive and 22 cases of syphilis infection were undertaken cordocentesis to get fetal umbilical blood samples. RESULTS The number of syphilis infection patient increased in recent years, the rate of RCH infection in normal pregnancy was lower （1.26 %） than that of in abortion patient （2.46 % ）, fetal malformation （28.54 % ） and stillbirth patient （5.26 % ）. Only one case of HSV-IgM positive was also found in fetal umbilical blood samples. 7 cases were RPR and TPHA positive and 15 cases were TPHA positive, while RPR was negative in fetal blood among total 22 patients with syphilis infection. CONCLUSION The vertical transmission of syphilis is more common than RCH in causing intrauterine infection.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第13期2667-2668,共2页
Chinese Journal of Nosocomiology
关键词
苍白密螺旋体
风疹病毒
巨细胞病毒
单纯疱疹病毒
宫内感染
Treponema pallidum
Rubella virus
Cytomegalovirus
Herpes simplex virus
Intrauterine infection
