期刊文献+

补阳还五汤联合贝那普利治疗早期糖尿病肾病30例 被引量:8

下载PDF
导出
摘要 目的评价补阳还五汤联合贝那普利治疗早期糖尿病肾病(DN)的疗效。方法将符合条件的60例DN患者随机分为对照组和治疗组,对照组单用贝那普利治疗,治疗组在对照组治疗基础上加服补阳还五汤,2组均治疗12周。比较2组治疗前后尿微量白蛋白排泄率(UAER)、空腹血糖(FBG)、餐后2 h血糖(2hPG)、糖化血红蛋白(HbAlc)和血压的变化。结果治疗后2组UAER、FBG、2hPG、HbAlc和血压较治疗前均有明显下降(P<0.01);治疗组UAER、血压较对照组下降更明显(P<0.01)。结论补阳还五汤联合贝那普利治疗早期DN疗效优于单用贝那普利。
作者 叶启铭 陈芳
机构地区 霞浦县中医院
出处 《福建中医药》 2011年第3期7-8,共2页 Fujian Journal of Traditional Chinese Medicine
  • 相关文献

参考文献8

二级参考文献54

  • 1Okada S, Shikata K, et al. Intercellular adhesion molecule-1-deficient mice are resistant against renal injury after induction of diabetes[J]. Diabetes, 2003 Oct,52(10) :2586. 被引量:1
  • 2Forbes JM, Cooper ME, et al. Role of advanced glycation end products in diabetic nephropathy[J]. J Am Soc Nephrol, 2003,14(8 Suppl 3):S254. 被引量:1
  • 3Omoto S, Nomura S, et al. Significance of platelet-derived microparticles and activated plate lets in diabetic nephropathy[J]. Nephron, 1999,81(3):271. 被引量:1
  • 4Li JM, Shah AM. ROS generation by nonphagocytic NADPH oxidase:potential relevance in diabetic nephropathy[J]. J Am Soc Nephrol, 2003 Aug, 14(8 Suppl 3):S221. 被引量:1
  • 5Ha H, Lee HB. Reactive oxygen species and matrix remodeling in diabetic kidney[J]. J Am Soc Nephrol, 2003 Aug, 14(8 Suppl 3) :S246. 被引量:1
  • 6Anjaneyulu M, Chopra K. Effect of Irbesartan on the Antioxidant Defence System and Nitric Oxide Release in Diabetic Rat Kidney[J]. Am J Nephrol, 2004 Sep 7,24(5) :488. 被引量:1
  • 7Onozato ML, Tojo A, et al. Oxidative stress and nitric oxide synthase in rat diabetic nephropathy:effects of ACEI and ARB[J]. Kidney Int, 2002 Jan,61(1) :186. 被引量:1
  • 8Baricos WH, Cortez SL, el-Dahr SS, et al. ECM degradation by cultured human mesangial cells is mediated by a PA/plasmin/MMP-2 cascade[J].Kidney Int, 1995,47(4): 1039. 被引量:1
  • 9McLennan SV, Yue DK, Tutle JR. Effect of gulose on matrix metalloproteinase activity in mesangial cells[J]. Nephron, 1998,79:293. 被引量:1
  • 10Chen S, Jim B, et al. Diabetic nephropathy and transforming growth factorbeta: transforming our view of glomerulosclerosis and fibrosis build-up.Ziyadeh FN[J]. Semin Nephrol, 2003 Nov,23(6):532. 被引量:1

共引文献507

同被引文献88

引证文献8

二级引证文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部