摘要
目的探讨血小板参数对慢性乙型肝炎(乙肝)肝硬化及肝功能评估的价值。方法 选取144例慢性乙肝肝硬化患者,其中血小板减少者114例[包括44例肝功能代偿者(A组)和70例肝功能失代偿者(B组)],血小板正常者30例(C组);另选取31例健康体检者作对照(D组)。4组受检者均空腹取血,检测并比较血小板参数[包括血小板计数(PLT)、血小板分布宽度(PDW)、血小板平均体积(MPV)、血小板压积(PCT)]。结果与D组比较,A、B、C组肝硬化患者的PLT均显著降低,而MPV均显著增高,差异有统计学意义(P<0.01)。A、B、C、D组受检者PDW比较,差异无统计学意义(P>0.05)。A、B组肝硬化患者PCT较C、D组均显著降低,差异有统计学意义(P<0.01)。结论血小板参数可以作为评价慢性乙肝肝硬化的指标,但不能评价肝硬化患者肝功能代偿与否。
Objective To investigate the Platelet parameter value in assessment of chronic type B hepatitis cirrhosis and liver function. Methods One hundred forty-four chronic type B hepatitis patients including 114 thrombocytopenia patients,who were divided into groups A,(n=44,with liver function compensation),B(n=70,with liver broken compensation),and 30 patients with normal platelet(group C),31 healthy subjects(group D) were enrolled to detect platelet parameters including platelet count(PLT),platelet distribution width(PDW),mean platelet volume(MPV),thrombocytocrit(PCT). Results PLT was significantly lower,MPV higher in groups A,B,C than in group D(P〈0.01).There was not significant difference in PDW between groups A,B,C,D(P〈0.05).PCT was lower in groups A,B than in groups C,D(P〉0.01). Conclusion Platelet parameter can be used as an index to evaluate Chronic type B hepatitis cirrhosis,but it can not be used to test cirrhosis functional compensation.
出处
《中国全科医学》
CAS
CSCD
北大核心
2011年第15期1699-1700,共2页
Chinese General Practice