摘要
目的:观察小剂量多巴胺及酚妥拉明治疗肺心病难治性心衰的临床疗效。方法:收集我院肺心病难治性心衰患者110例,随机分为对照组55例,治疗组55例,基础治疗均采用限钠,限水,持续低流量吸氧,积极抗感染,畅通气道,平喘,强心,利尿,纠正水电解质平衡;治疗组在常规治疗基础上加用小剂量多巴胺,酚妥拉明,比较2组的疗效。结果:治疗组显效42例,有效9例,无效4例,总有效率92.7%。对照组显效40例,有效8例,无效7例,总有效率87.3%。两组治疗后均优于治疗前,治疗组明显优于对照组(P<0.05),差异有统计学意义。结论:在常规治疗肺心病难治性心衰基础上,联合使用小剂量多巴胺、酚妥拉明可改善症状,提高疗效,优于单纯使用洋地黄制剂改善心衰症状。
Objective： To observe the low-dose dopamine and phentolamine in the treatment of pulmonary heart disease with refractory heart failure in clinical efficacy.Methods：pulmonary heart disease in our hospital 110 patients with refractory heart failure, 55 patients were randomly divided into control group, treatment group 55 cases, the basis of treatment are used sodium restriction, water restriction, continuous low flow oxygen, active anti-inflammatory and smooth airway, asthma, cardiac, diuretic, correct water and electrolyte balance; treatment group on the basis of conventional therapy plus low-dose dopamine, phentolamine, compared 2 groups of patients.Results：The treatment group 42 cases, effective in 9 cases, 4 cases, total effective rate 92.7%. Control group, 40 cases markedly effective, 8 cases, 7 cases, total effective rate 87.3%. After treatment, are better than before treatment, the treatment group than the control group （P〈0.05）, the difference was statistically significant.Conclusion：The conventional treatment of refractory heart failure, pulmonary heart disease based on the combined use of small doses of dopamine, phentolamine can improve symptoms, improve the efficacy, better than the simple use of digitalis preparations to improve heart failure symptoms.
出处
《中国医药导刊》
2011年第4期633-634,共2页
Chinese Journal of Medicinal Guide
关键词
多巴胺
酚妥拉明
肺心病
难治性心衰
Dopamine
Phentolamine
Pulmonary heart disease
Refractory heart failure
