摘要
目的 研究脑血管性痴呆（ Ｖ Ｄ） 与帕金森病（ Ｐ Ｄ） 在神经心理学测验及脑单光子发射计算机断层扫描（ Ｓ Ｐ Ｅ Ｃ Ｔ） 的诊断和鉴别诊断的意义。方法 对３０ 例 Ｖ Ｄ、３１ 例 Ｐ Ｄ 和３０ 名正常老年人（ Ｎ Ａ） 进行神经心理学测验和 Ｓ Ｐ Ｅ Ｃ Ｔ 检查并比较检测结果。结果 神经心理学各项总分 Ｖ Ｄ 组最低［ 除积木测验（ Ｂ Ｄ） 外］ ， Ｐ Ｄ 组次之， Ｎ Ａ 组最高；３ 组间差异均有非常显著性（ Ｆ＝ １８６７ ～６３９５ ， Ｐ＜００１） 。在 Ｓ Ｐ Ｅ Ｃ Ｔ的检查中， Ｖ Ｄ 除额叶、左丘脑和右枕叶外余各脑区血流灌注均低于 Ｎ Ａ 组（ Ｐ＜００５） ， Ｐ Ｄ 则为顶叶、颞叶、基底节和丘脑血流灌注低于 Ｎ Ａ 组（ Ｐ＜ ００５） 。结论 Ｖ Ｄ 和 Ｐ Ｄ 的神经心理学测验和脑 Ｓ Ｐ Ｅ Ｃ Ｔ各有其特点，这两项检查可作为诊断和鉴别诊断 Ｖ Ｄ 和 Ｐ Ｄ 的辅助手段。
Objective To explore the diagnostic characteristics of neuropsychological tests and brain SPECT in the patients with vascular dementia (VD) and Parkinson′s disease (PD) Methods Five neuropsychological tests and SPECT were performed in 30 normal aged (NA) subjects, 30 patients with VD and 31 patients with PD to compare the difference in cognitive functions and cerebral perfusion Results Cognitive functions assessed by neuropsychological tests showed NA>PD>VD The cognitive impairment mode of VD was similar to PD The cerebral perfusion of VD was significantly decreased compared to that of NA in frontal, left thalamus and right occipital cortex The perfusion was asymmetrical in VD, with a significant decrease in left parietal, left temporal and right thalamus Conclusions Neuropsychological tests and brain SPECT are helpful in the diagnosis and differentiation between VD and PD
出处
《中华精神科杂志》
CSCD
1999年第3期145-147,共3页
Chinese Journal of Psychiatry
关键词
痴呆
血管性痴呆
震颤性麻痹
SPECT
神经心理学
Dementia
vascular
Parkinson disease
Tomography
emission computed
single photon
Neuropsychological tests
