期刊文献+

宫颈胰岛素样生长因子结合蛋白-1对分娩预测的研究

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摘要 目的探讨宫颈分泌物中胰岛素样生长因子结合蛋白-1(IGFBP-l)对分娩预测的作用。方法对200例妊娠37~41周、未临产、胎膜完整的孕妇,采用免疫层析法进行宫颈分泌物IGFBP-l测定,比较IGFBP-1和宫颈评分预测72小时内分娩的成功性。结果宫颈分泌物中IGFBP-l预测72小时内分娩的敏感性、特异性、阳性预测值和阴性预测值分别是99.1%、92.14%、91.52%、97.56%,与宫颈Bishop评分比较,有较高的预测价值。结论宫颈分泌物IGFBP-l不仅反映宫颈成熟度,也反映子宫下段的生理变化过程,可作为产程发动的指标,且不依赖于临床经验,对于指导临床进行必要的产科处理具有实际意义。
出处 《中国医刊》 CAS 2011年第6期84-86,共3页 Chinese Journal of Medicine
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