摘要
目的:研究八角科Illiciaceae植物野八角Illicium simonsii茎叶的化学成分。方法:应用硅胶、Sephadex LH-20,Rp-C8,Rp-C18等各种色谱技术进行分离纯化,根据化合物的理化常数和波谱数据鉴定其结构。结果:从野八角茎叶的95%乙醇提取物中分离得到14个化合物,通过波谱数据和理化常数分别鉴定为ficusesquilignan A(1),醉鱼草醇C(2),醉鱼草醇D(3),leptolepisol A(4),acernikol(5),aviculin(6),山柰酚(7),槲皮素(8),槲皮素-3-O-α-L-吡喃鼠李糖苷(9),花旗松素-3-O-β-D-吡喃木糖苷(10),benzyl-2-O-β-D-glucopyranosyl-2,6-dihydroxybenzoate(11),2,4-dihydroxy-3,6-dimethyl-methyl-benzoate(12),biondinin C(13),莽草酸(14)。结论:除化合物9,14外,其余化合物均为首次从该植物中分离得到。
Objective： To study the chemical constituents of the Illicium simonsii.Method： The stems and leaves of I.simonsii were extracted with 95%EtOH.The EtOH extract was dispersed in H2O and extracted with petroleum,CHCl3 and BuOH,successively.The CHCl3 and BuOH fractions were isolated and purified by column chromatography on silica gel,Sephadex LH-20,Rp-C8 and Rp-C18.The isolated compounds were identified on the basis of spectral analyses（including MS,1H-NMR,13C-NMR）.Result： Fourteen compounds were isolated from the stems and leaves of I.simonsii,which were characterized as ficusesquilignan A（1）,buddlenol C（2）,buddlenol D（3）,leptolepisol A（4）,acernikol（5）,aviculin（6）,kaempferol（7）,quercetin（8）,quercetin 3-O-α-L-rhamnopyranosyl-（1→6）-β-D-glucopyranoside（9）,taxifolin-3-O-β-D-xylopyranoside（10）,benzyl-2-O-β-D-glucopyranosyl-2,6-dihydroxybenzoate（11）,2,4-dihydroxy-3,6-dimethyl-methylbenzoate（12）,biondinin C（13）,shikimic acid（14）.Conclusion： Except compounds 9 and 14,all the other compounds were obtained from I.simonsii for the first time.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2011年第10期1311-1315,共5页
China Journal of Chinese Materia Medica
关键词
八角属
野八角
木脂素
黄酮
化学成分
lUicium
lllicium simonsii
lignans
flavonoids
chemical constituents
