摘要
由于抗生素的不合理使用导致细菌耐药性越来越严重.医院所有细菌中耐药菌的分离率明显增加,交叉感染越来越严重,抗生素对多重耐药菌(对三种以上抗生素耐药)效果不理想,而中药在抗细菌耐药性方面有突出作用.在努力研发抗耐药性细菌的新的抗生素的同时,应加大对具有良好抗菌活性的中药的开发力度.对细菌耐药性产生的外界因素(药物滥用);细菌对各类主要抗生素(β-内酰胺类、氨基糖苷类、喹诺酮类及万古霉素)产生耐药性的内在机制;化学药物与中药对耐药性细菌的控制措施及其近年来的研究作以阐述.
Bacteria drug resistance is becoming more and more serious for the reason of drug abuse.The percentage of drug resistance bacteria separation in hospital is growing obviously,and the cross infection is more and more serious,the efficacy of the antibiotics for multiplex drug resistance bacteria is not pleased,the effectiveness of antibiotics to the bacteria of drug resistance is getting worse and worse.This paper explained the causes of drug abuse,the inner mechanism of the main kinds of the antibiotics,control measures and the progress for chemotherapy and the traditional Chinese medicine of bacteria drug resistance were reviewed and analyzed.
出处
《哈尔滨商业大学学报（自然科学版）》
CAS
2011年第2期148-150,共3页
Journal of Harbin University of Commerce：Natural Sciences Edition
基金
国家十一五重大新药创制科技专项(2009x09103-358)
黑龙江省教育厅科技专项资助(11531345)
关键词
细菌耐药性
产生机制
控制措施
中药
bacteria drug resistance
mechanism
control measures
Chinese medicine
