摘要
目的 通过对角膜前表面波阵面的测量,研究配戴RGPCL及停戴之后角膜前表面的形态变化.方法 临床观察.使用客观波阵面仪测量30人（60只眼）在配戴RGPCL之前及停戴之后的30 min及1、3、7、14 d后的角膜前表面像差,并进行各时间点的对照分析.对停戴后各时间点、各像差项及各组间进行方差分析、配对t检验.结果 配戴RGPCL前、停戴后30 min及1、3、7、14 d时配戴者双眼角膜前表面7阶32项Zernike像差均方根值分别为1.438±0.328,1.076±0.355、1.362±0.402、1.373±0.398、1.387±0.415及1.448±0.423.其中停戴30 min时,2阶、3阶像差几乎全部改变（Z3、Z4、Z5、Z6、Z7、Z8）,4阶中的四叶草（quadrafoil Z10）和球差（spherical Z12）2项改变,这些改变中除Z8、Z9、Z10增大外,其余均为减少.停戴后1 d相比配戴前,Z5、Z6减少,Z12比戴前有所增加（F=2.869～5.549,P=0.001～0.042）.停戴后3 d,Z5、Z6依然比配戴前减少,而Z9和Z10又再次出现增加,Z12恢复到配戴前水平.停戴7 d后,只有Z6和Z9略有改变,其余均恢复至配戴前.停戴14 d时各阶像差与配戴前已无变化（F=0.018～1.876,P=0.154～0.650）.结论 配戴RGPCL能显著减少角膜前表面总像差,这种改变在停戴后30 min最为明显,随着停戴时间延长慢慢减少,低阶像差基本都在较短时间内恢复戴前水平,在恢复过程中可能会产生一过性的高阶像差,但所有改变均在停戴2周内停止.
Objective The present study used a corneal topographic device to record aberrations on the anterior surface of the cornea at different time-points prior to wearing and following discontinued use of rigid gas permeable （RGP） contact lenses. The effect of wearing RGPCL on the anterior surface of the cornea was discussed to provide guidance for clinical refractive error correction. Methods The study objects were 60 eyes from 30 patients. All patients underwent identical examination procedures prior to lens use, as well as afterwards, including slit-lamp examination, non-contact tonometer measurement, computer optometry ＆ corneal curvature measurement, subjective refraction test, and corneal topography analysis. The patients wore contact lenses every day for 1 month and then discontinued. Corneal topographies were recorded at certain time points of 30 min, 1 day, 3 days, 1 week, and 2 weeks following use. Results Total corneal aberration at each time point following discontinued use of RGP contact lenses was less than the time point prior to use. Detailed results are as follows; root mean square （RMS） （pre） = （1.438 ±0.328）, RMS （30 min） = （1.076 ± 0.355）, RMS （1 day） = （1.362 ± 0.402） , RMS （3 day） =（1.373 ± 0.398）, RMS （7 day） = （1.387 ± 0.415）, and RMS （14 day） = （1.448 ± 0.423） .Results showed that at 30 minutes after discontinued use of RGP contact lenses, almost all 2nd-and 3rd-order aberrations were altered. Quadrafoil Z10 and spherical Z12 of the 4th-order were also changed. Alterations to Z5, Z6, and Z12 at 1 day after discontinued use were significant compared with the time period prior to RGP use： Z5 and Z6 decreased, and Z12 increased slightly（ F =2. 869 ～5. 549 ,P =0. 001 ～0. 042）. Z5 and Z6remained decreased at 3 days after discontinued use, but Z9 and Z10 continued to increase and Z12 returned to levels prior to RGP use （ P ＞ 0. 05 ）. At 2 weeks after discontinued use, all aberrations were not significantly different from t
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2011年第4期327-331,共5页
Chinese Journal of Ophthalmology
关键词
像差
接触镜
角膜
Aberration
Contact lenses
Cornea
